Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 30

Faculty Files
Figure 2. Nonsurgical expansion of the maxillary arch using Invisalign clear aligners and Aevo System (LIPUS;
SmileSonica Inc., Edmonton, AB, Canada) in a 37-year-old woman. The treatment time was 18 months, with the
patient changing aligners every 3-5 days
remodeling during experimental orthodontic tooth
movement in beagle dogs. The results showed that
not only did LIPUS enhance the repair of OITRR, but
it also accelerated orthodontic tooth movement in
beagle dogs, which is the animal model most similar
to humans.6
may accelerate orthodontic tooth movement.
The next logical step was to perform double-blinded
controlled clinical trials in humans to test the hypothesis
that LIPUS may accelerate tooth movement. This
multicenter clinical trial was performed and recently
published, showing that LIPUS can accelerate orthodontic
tooth movement in humans when performed
with fixed orthodontic appliances.7
This accelerated
tooth movement was augmented when combined
with clear aligner treatment.8
A third accidental discovery that I encountered while
doing my PhD was that LIPUS can also enhance
mandibular growth in rabbits.9
A subsequent higher
animal study in monkeys showed that LIPUS and
bite jumping appliances can work synergistically to
enhance mandibular growth,10
and a pilot study in
This was the second discovery that LIPUS
patients with hemifacial microsomia confirmed this
effect.11
The challenge was that it took more than a
year to observe the clinical effect in humans; thus,
optimization studies are needed to potentially minimize
treatment time. Presently, these optimization
studies are still being conducted in lower animals,12-19
and to transfer these data to clinical trials would
require intermediary higher animal studies, which
is not currently feasible in North America. However,
LIPUS still holds promise in its potential therapeutic
effect on bone remodeling. The future of this technology
may see more case reports, case series, and
clinical trials to support or provide alternative results.
It is to be noted that LIPUS application is technique
sensitive and must be correctly applied to obtain
clinically meaningful results.
Figure 3. A 33-year-old man with skeletal class II division 2, treated with Invisalign and Aevo System (LIPUS) for
a treatment time of 19 months. Pretreatment photos (left) versus posttreatment photos (middle), with superimposition
(right) demonstrating a correction of deep bite by leveling the mandibular curve of Spee and allowing
forward rotation of the mandible that corrected the class II malocclusion
30
PCSO Bulletin Spring 2022

Pacific Coast Society of Orthodontists Bulletin Spring 2022

Table of Contents for the Digital Edition of Pacific Coast Society of Orthodontists Bulletin Spring 2022

Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 1
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 2
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 3
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 4
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 5
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 6
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 7
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 8
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 9
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 10
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 11
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 12
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 13
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 14
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 15
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 16
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 17
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 18
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 19
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 20
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 21
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 22
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 23
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 24
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 25
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 26
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 27
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 28
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 29
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 30
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 31
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 32
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 33
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 34
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 35
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 36
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 37
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 38
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 39
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 40
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 41
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 42
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 43
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 44
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 45
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 46
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 47
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 48
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 49
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 50
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 51
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 52
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 53
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 54
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 55
Pacific Coast Society of Orthodontists Bulletin Spring 2022 - 56
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