Baylor University Medical Center Proceedings October 2017 - 407
Table 1. (Continued )
Variable
Femoral (n = 30)
Radial (n = 30)
5
0 (0%)
7 (24%)
6
19 (63%)
22 (76%)
7
6 (20%)
0 (0%)
8
5 (17%)
0 (0%)
1
1 (3%)
2 (7%)
2
10 (33%)
8 (27%)
3
10 (33%)
18 (60%)
4
5 (17%)
1 (3%)
5
4 (13%)
1 (3%)
3 (1-5)
3 (1-5)
0.33
138.5 ± 27.9
132.9 ± 25.0
0.43
Arterial sheath size
P value
<0.001
Number of catheter exchanges
0.12
Catheter exchanges: median (range)
Postprocedure
Systolic BP (mm Hg): mean ± SD
Diastolic BP (mm Hg): mean ± SD
74.6 ± 10.7
75.6 ± 15.3
0.78
Heart rate (bpm): median (range)
85 (46-119)
78 (48-177)
0.34
ACS indicates acute coronary syndrome; BMI, body mass index; BP, blood pressure; BUN, blood urea nitrogen;
CVA, cerebrovascular accident; eGFR, estimated glomerular filtration rate; IABP, intra-aortic balloon pump; PCI,
percutaneous coronary intervention; TIA, transient ischemic attack; catheter exchange, number of catheter
exchanges done over the wire during the procedure.
associated with protecting the myocardium from
ischemic injury as well as in reducing infarct size
(16). Further, a positive association has been
found between HSP27 and medullary perfusion
in patients with kidney allografts, and HSP27
has been identified as a diagnostic marker for renal cell carcinoma (17). In our study, we found
higher levels of HSP27 in women than in men.
Studies have reported higher levels of urinary
thioredoxin in women and have noted that the
increased urinary excretion is influenced by an
estrogen-mediated mechanism (8). Increased
urinary thioredoxin has further been identified
as a potential marker for diabetic nephropathy
(8) and AKI (18). In our study, the exploratory
analysis showed higher levels of thioredoxin in
women than in men (P = 0.0002 preprocedure;
P = 0.0008 postprocedure). We also found a
significant decrease in the levels of thioredoxin
postprocedure, irrespective of approach.
Taurine has been identified to be involved in
neuronal modulation, osmoregulation, and protection against oxidative stress (19). Taurine was
found to be excreted in excess following surgery,
peaking on the second or third day postsurgery.
Table 2. Urinary metabolites by baseline characteristics and demographics
Heat shock protein 27
Thioredoxin
Taurine
Talose
Variable
Pre
Gender
0.0001
0.0002
0.0008
0.03
0.02
0.84
Diabetes
0.42
0.66
0.62
0.28
0.29
0.81
<0.001
Hypertension
0.97
0.18
0.64
0.48
0.13
0.42
Dyslipidemia
0.03
0.12
0.03
0.07
0.54
PAD
0.49
0.11
0.78
0.24
0.25
Heart failure
0.65
0.34
0.39
0.73
Catheter exchange >3
0.78
0.52
0.17
0.47
Arterial sheath >6
0.76
0.32
0.4
Age
(rho, P value)
-0.005
(0.97)
0.07
(0.62)
Total contrast used
(rho, P value)
-0.078
(0.56)
Fluoroscopy time
(rho, P value)
Post
<0.001
Pre
Post
Pre
Post
Pre
Sulfuric acid
Post
Pre
Post
0.26
0.04
0.34
0.0001
0.44
0.28
0.66
0.17
0.39
0.97
0.71
0.17
0.11
0.001
0.72
0.33
0.77
0.51
0.79
0.19
0.26
0.58
0.46
0.49
0.34
0.07
0.89
0.45
0.007
0.009
0.17
0.61
0.45
0.8
0.45
0.07
0.11
0.67
0.46
0.003
(0.98)
0.09
(0.49)
0.21
(0.10)
0.16
(0.21)
0.006
(0.96)
-0.01
(0.92)
0.04
(0.77)
-0.03
(0.84)
-0.03
(0.80)
-0.16
(0.24)
-0.22
(0.09)
0.02
(0.86)
0.07
(0.59)
0.05
(0.69)
0.03
(0.84)
0.04
(0.74)
-0.27
(0.04)
-0.08
(0.51)
0.08
(0.56)
0.12
(0.44)
-0.15
(0.25)
-0.02
(0.87)
0.11
(0.40)
0.07
(0.60)
0.11
(0.40)
0.11
(0.40)
-0.18
(0.17)
Total fluoroscopy
dose (rho, P value)
-0.22
(0.09)
-0.21
(0.11)
-0.21
(0.12)
-0.25
(0.05)
-0.04
(0.74)
0.02
(0.88)
0.02
(0.88)
0.11
(0.39)
0.14
(0.29)
-0.11
(0.41)
BMI
(rho, P value)
-0.03
(0.85)
-0.12
(0.37)
-0.07
(0.59)
0.09
(0.47)
-0.08
(0.54)
-0.18
(0.18)
0.02
(0.89)
0.06
(0.67)
0.13
(0.32)
0.13
(0.32)
LVEF
(rho, P value)
0.25
(0.09)
0.16
(0.28)
-0.03
(0.84)
0.16
(0.27)
-0.13
(0.40)
-0.15
(0.32)
-0.10
(0.49)
-0.21
(0.16)
-0.05
(0.70)
-0.25
(0.09)
eGFR
(rho, P value)
0.08
(0.57)
0.26
(0.06)
-0.13
(0.35)
0.17
(0.22)
0.15
(0.26)
0.10
(0.46)
0.08
(0.54)
0.04
(0.76)
-0.07
(0.62)
-0.02
(0.90)
BMI indicates body mass index; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; PAD, peripheral arterial disease.
October 2017
Metabolites and arterial access
407
Table of Contents for the Digital Edition of Baylor University Medical Center Proceedings October 2017
No label
Baylor University Medical Center Proceedings October 2017 - No label
Baylor University Medical Center Proceedings October 2017 - Cover2
Baylor University Medical Center Proceedings October 2017 - 393
Baylor University Medical Center Proceedings October 2017 - 394
Baylor University Medical Center Proceedings October 2017 - 395
Baylor University Medical Center Proceedings October 2017 - 396
Baylor University Medical Center Proceedings October 2017 - 397
Baylor University Medical Center Proceedings October 2017 - 398
Baylor University Medical Center Proceedings October 2017 - 399
Baylor University Medical Center Proceedings October 2017 - 400
Baylor University Medical Center Proceedings October 2017 - 401
Baylor University Medical Center Proceedings October 2017 - 402
Baylor University Medical Center Proceedings October 2017 - 403
Baylor University Medical Center Proceedings October 2017 - 404
Baylor University Medical Center Proceedings October 2017 - 405
Baylor University Medical Center Proceedings October 2017 - 406
Baylor University Medical Center Proceedings October 2017 - 407
Baylor University Medical Center Proceedings October 2017 - 408
Baylor University Medical Center Proceedings October 2017 - 409
Baylor University Medical Center Proceedings October 2017 - 410
Baylor University Medical Center Proceedings October 2017 - 411
Baylor University Medical Center Proceedings October 2017 - 412
Baylor University Medical Center Proceedings October 2017 - 413
Baylor University Medical Center Proceedings October 2017 - 414
Baylor University Medical Center Proceedings October 2017 - 415
Baylor University Medical Center Proceedings October 2017 - 416
Baylor University Medical Center Proceedings October 2017 - 417
Baylor University Medical Center Proceedings October 2017 - 418
Baylor University Medical Center Proceedings October 2017 - 419
Baylor University Medical Center Proceedings October 2017 - 420
Baylor University Medical Center Proceedings October 2017 - 421
Baylor University Medical Center Proceedings October 2017 - 422
Baylor University Medical Center Proceedings October 2017 - 423
Baylor University Medical Center Proceedings October 2017 - 424
Baylor University Medical Center Proceedings October 2017 - 425
Baylor University Medical Center Proceedings October 2017 - 426
Baylor University Medical Center Proceedings October 2017 - 427
Baylor University Medical Center Proceedings October 2017 - 428
Baylor University Medical Center Proceedings October 2017 - 429
Baylor University Medical Center Proceedings October 2017 - 430
Baylor University Medical Center Proceedings October 2017 - 431
Baylor University Medical Center Proceedings October 2017 - 432
Baylor University Medical Center Proceedings October 2017 - 433
Baylor University Medical Center Proceedings October 2017 - 434
Baylor University Medical Center Proceedings October 2017 - 435
Baylor University Medical Center Proceedings October 2017 - 436
Baylor University Medical Center Proceedings October 2017 - 437
Baylor University Medical Center Proceedings October 2017 - 438
Baylor University Medical Center Proceedings October 2017 - 439
Baylor University Medical Center Proceedings October 2017 - 440
Baylor University Medical Center Proceedings October 2017 - 441
Baylor University Medical Center Proceedings October 2017 - 442
Baylor University Medical Center Proceedings October 2017 - 443
Baylor University Medical Center Proceedings October 2017 - 444
Baylor University Medical Center Proceedings October 2017 - 445
Baylor University Medical Center Proceedings October 2017 - 446
Baylor University Medical Center Proceedings October 2017 - 447
Baylor University Medical Center Proceedings October 2017 - 448
Baylor University Medical Center Proceedings October 2017 - 449
Baylor University Medical Center Proceedings October 2017 - 450
Baylor University Medical Center Proceedings October 2017 - 451
Baylor University Medical Center Proceedings October 2017 - 452
Baylor University Medical Center Proceedings October 2017 - 453
Baylor University Medical Center Proceedings October 2017 - 454
Baylor University Medical Center Proceedings October 2017 - 455
Baylor University Medical Center Proceedings October 2017 - 456
Baylor University Medical Center Proceedings October 2017 - 457
Baylor University Medical Center Proceedings October 2017 - 458
Baylor University Medical Center Proceedings October 2017 - 459
Baylor University Medical Center Proceedings October 2017 - 460
Baylor University Medical Center Proceedings October 2017 - 461
Baylor University Medical Center Proceedings October 2017 - 462
Baylor University Medical Center Proceedings October 2017 - 463
Baylor University Medical Center Proceedings October 2017 - 464
Baylor University Medical Center Proceedings October 2017 - 465
Baylor University Medical Center Proceedings October 2017 - 466
Baylor University Medical Center Proceedings October 2017 - 467
Baylor University Medical Center Proceedings October 2017 - 468
Baylor University Medical Center Proceedings October 2017 - 469
Baylor University Medical Center Proceedings October 2017 - 470
Baylor University Medical Center Proceedings October 2017 - 471
Baylor University Medical Center Proceedings October 2017 - 472
Baylor University Medical Center Proceedings October 2017 - 473
Baylor University Medical Center Proceedings October 2017 - 474
Baylor University Medical Center Proceedings October 2017 - 475
Baylor University Medical Center Proceedings October 2017 - 476
Baylor University Medical Center Proceedings October 2017 - 477
Baylor University Medical Center Proceedings October 2017 - 478
Baylor University Medical Center Proceedings October 2017 - 479
Baylor University Medical Center Proceedings October 2017 - 480
Baylor University Medical Center Proceedings October 2017 - 481
Baylor University Medical Center Proceedings October 2017 - 482
Baylor University Medical Center Proceedings October 2017 - 483
Baylor University Medical Center Proceedings October 2017 - 484
Baylor University Medical Center Proceedings October 2017 - 485
Baylor University Medical Center Proceedings October 2017 - 486
Baylor University Medical Center Proceedings October 2017 - 487
Baylor University Medical Center Proceedings October 2017 - 488
Baylor University Medical Center Proceedings October 2017 - 489
Baylor University Medical Center Proceedings October 2017 - 490
Baylor University Medical Center Proceedings October 2017 - 491
Baylor University Medical Center Proceedings October 2017 - 492
Baylor University Medical Center Proceedings October 2017 - Cover3
Baylor University Medical Center Proceedings October 2017 - Cover4
http://www.brightcopy.net/allen/bapr/30-4
http://www.brightcopy.net/allen/bapr/30-3
http://www.brightcopy.net/allen/bapr/30-2
http://www.brightcopy.net/allen/bapr/30-1
http://www.brightcopy.net/allen/bapr/29-4
http://www.brightcopy.net/allen/bapr/29-3
http://www.brightcopy.net/allen/bapr/29-2
http://www.brightcopy.net/allen/bapr/29-1
http://www.brightcopy.net/allen/bapr/28-04
https://www.nxtbook.com/allen/bapr/28-3
https://www.nxtbook.com/allen/bapr/28-2
https://www.nxtbook.com/allen/bapr/28-1
https://www.nxtbook.com/allen/bapr/27-4
https://www.nxtbook.com/allen/bapr/27-3
https://www.nxtbookmedia.com