Baylor University Medical Center Proceedings October 2017 - 470

University Medical Center. While esophagus
problems are common, not many programs offer specialized training in this area, so it provides
an educational opportunity for future gastroenterologists.
■ Baylor Scott & White - Grapevine,

Tarrant County EMS teams adopt
Pulsara
Patients experiencing a heart attack or
stroke can benefit from a new communication
technology, Pulsara, a smartphone app implemented by 11 northeast Tarrant emergency
medical services (EMS) teams and Baylor Scott
& White Medical Center - Grapevine.
The hospital is the first in the Baylor Scott
& White Health system and the first in Tarrant
County to implement smartphone technology to
support care for these patients. The app allows
EMTs in the field who recognize symptoms of
a stroke or heart attack to simply tap a button on their smartphones. This tap notifies the
hospital team that an ambulance is on its way
with a critical patient. As the paramedic enters
more information, such as the patient's medical history and vital signs, every team member
receives a secure update. To date, the hospital
has used the technology for a possible 115
myocardial infarctions and 117 strokes.
■ Brain and Spine Center at Baylor

Scott & White Medical Center - Plano
opens
A new center dedicated to brain and spine
services has opened at Baylor Scott & White
Medical Center - Plano. The Brain and Spine
Center offers comprehensive care within
both medical and surgical specialties. Some

470

of these services are brain tumor surgery,
movement disorders and epilepsy treatment,
neuromodulation, complex spine surgery,
minimally invasive spine surgery, peripheral
nerve disorders treatment, and headache and
stroke care.
"Our community has indicated they want to
have these highly specialized services available
here in Plano," said Jerri Garison, president,
Baylor Scott & White - Plano. "We built a
strong team of physicians and specialty certified
nurses to care for patients with these complex
neurological and neurosurgical diseases."
The neurosurgeons and neurointerventional
radiologists on the medical staff at Baylor Scott
& White - Plano specialize in minimally invasive surgical techniques. The hospital uses
the StealthStation surgical navigation system,
which enables neurosurgeons to precisely
track the location of surgical instruments
throughout a procedure. The StealthStation
system introduces an advanced version of
Stealth technology-a combination of hardware, software, tracking algorithms, image
data merging, and specialized instruments to
help guide them during surgical procedures
such as biopsy, tumor resection, and deep
brain stimulation lead placement. A new epilepsy monitoring unit is part of the hospital's
expansion of its intensive care unit to 32 beds
from 16 beds. Four beds in the new unit will
be dedicated to epilepsy monitoring.
■ Researchers show curcumin

protects against chemoresistant
pancreatic cancer
Curcumin is known for its powerful antiinflammatory and antioxidant benefits, but a

Baylor University Medical Center Proceedings

new study by researchers at Baylor Scott &
White Research Institute reveals an additional
benefit: its potential to overcome chemoresistance in pancreatic ductal adenocarcinoma
(PDAC), a common but aggressive form of
cancer in the pancreas.
The study, "Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1
expression," was published in Carcinogenesis.
Previous research demonstrated the advantages of taking curcumin preventatively, but
this is the first study of its kind to demonstrate benefits of curcumin as an adjunct to
chemotherapy.
Resistance to chemotherapeutic drugs is
a major challenge in caring for patients with
PDAC, the fourth leading cause of cancerrelated deaths in the US. Patients may respond to chemotherapy initially, but as cancer
stem cells form, the body can develop drug
resistance. Now, researchers have developed
an improved understanding of the molecular
events underlying the development of pancreatic stem cells and the role that curcumin-
the main component of turmeric-plays in
overcoming resistance to vital chemotherapy
drugs.
"By treating certain cells with small
doses of curcumin, we were able to reverse
the pathways that lead to chemoresistance,"
said Ajay Goel, PhD, director of gastrointestinal research and translational genomics and
oncology at Baylor Scott & White Research
Institute and author of the study. "This is an
important breakthrough that could lead to
better prognosis and longer lives for patients
with chemoresistant pancreatic cancer." 

Volume 30, Number 4



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